Genetically engineered human pluripotent stem cells, functionalized silk-fibroin platforms and bio-inks: a novel solution for large-scale ex-vivo platelet production, transfusion and drug research

SilkFusion aims at building a model of the bone marrow, a 3D silk-fibroin technology for ex-vivo large-scale production of blood platelets for human transfusion. In addition, the system developed within SilkFusion can be used for testing cells from patients, to understand the mechanism of diseases and see if it is possible to find new therapeutically targets for platelet related diseases.